CEA-Scan (Immunomedics Inc)

CEA-Scan (Immunomedics Inc) - General Information

Reduced Fab fragment of the murine IgG1 monoclonal antibody IMMU-4 (also called NP-4) with specificity for carcinoembryonic antigen (CEA) covalently labeled with Technitium 99. The molecule has a molecular weight of ~54,000 Daltons.

Pharmacology of CEA-Scan (Immunomedics Inc)

Binds to the carcinoembryonic antigen, which is a cell surface protein generally overexpressed in colon (and other) cancers. The radioactive Tc99, which is covalently attached to the antibody, allows radiodiagnostic detection of CEA expressing cells and tumors

Additional information about CEA-Scan (Immunomedics Inc)

CEA-Scan (Immunomedics Inc) Indication: For imaging colorectal tumors
Mechanism Of Action: Binds selectively to cell-surface carcinoembryonic antigen (CEA) expressed on colorectal tumors.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Arcitumomab
Synonyms: CEA-Scan
Drug Category: Diagnostic Agents; Imaging Agents
Drug Type: Biotech; Approved; Investigational

Other Brand Names containing Arcitumomab: CEA-Scan (Immunomedics Inc);
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Most likely removed by opsonization via the reticuloendothelial system, or by human antimurine antibody production
Half Life: ~1 hours
Dosage Forms of CEA-Scan (Immunomedics Inc): Not Available
Chemical IUPAC Name: AntiCEA antibody
Chemical Formula: C6398H9900N1714O1995S54
Arcitumomab on Wikipedia: https://en.wikipedia.org/wiki/Arcitumomab
Organisms Affected: Not Available